"Wait and See"
Isn't a Treatment Plan.

H.O.P.E.® is MaxWell Clinic's patented advancement of therapeutic plasma exchange, a therapy trusted for decades, now used to help the body and brain repair by cleaning the blood they depend on. Performed at the largest private outpatient apheresis center in the United States.

Download H.O.P.E. Brochure
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Get a Team.
Not a Billing Code.

MaxWell Care surrounds you with a dedicated Clinician, Dietician, and Advocate who take the time to listen, test deeper than standard panels, and treat the root cause instead of managing symptoms.

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David Haase, MD, FMCP-M, QIA
CEO & Founder

Meet Dr. David Haase, the physician other doctors send their patients to for plasma exchange.

Vanderbilt-trained, Mayo Clinic residency, lead faculty at the Institute for Functional Medicine. Dr. Haase has spent more than a decade asking a different question about degenerative and autoimmune disease: what if part of the problem isn’t only in the brain or the body, but in the blood that feeds them? That question led to H.O.P.E.®, pioneered at MaxWell Clinic in 2019 and now performed over 1,000 times at the largest private outpatient apheresis center in the country.

Download H.O.P.E. Brochure
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However You Got Here, It Probably Sounds Like One of These.

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The Family History

You know what this disease did to your mother, your brother, your grandfather. And you've been told to eat well, stay active, and hope.

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The Changes You've Noticed

Names that won't surface. The forehead resting in the hands. A temper that was never there before. You see it, even when the doctors say it's early.

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"There's Nothing More We Can Do"

An autoimmune or neurological diagnosis, a prescription to manage it, and a follow-up in six months. That's the whole plan.

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The Long Recovery That Never Finishes

Since the illness (or the infection, or COVID), your energy, clarity, and strength never fully came back. The labs say you're fine.

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The Watching and Waiting

Every appointment measures the decline. None of them try to change it. You're not being treated; you're being tracked.

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The Not-Knowing

Is it working? Is it worse? Without real testing, every good day feels like guessing and every bad day feels like the beginning.

H.O.P.E. was built to do the opposite.

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Solution

When We Clean the Blood, the Body and Brain Work Better.

Your cells live in an environment: your plasma. As we age, or fight autoimmune disease, or carry a toxic or post-viral burden, that environment fills with aged proteins, auto-antibodies, and inflammatory molecules that work against repair. Therapeutic plasma exchange has been removing those from the blood since the 1950s; it’s a trusted standard of care for serious autoimmune and neurological conditions. H.O.P.E.® takes it further, replacing what’s removed with a solution built for your biology, so your cells get a healthier habitat to heal in.

  • A decades-proven therapy, advanced.
  • Personalized replacement, not just removal.
  • Measured with before-and-after testing, so progress isn't a feeling. It's data.
Download H.O.P.E. Brochure

Medicine the Way You Always Assumed It Worked.

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Remove

Using an IV in your arm, blood is drawn into a state-of-the-art apheresis machine. Each outpatient session takes 2 to 4 hours; most patients read, rest, or listen to music.

listen

Clean

The machine separates your aged, polluted plasma from your blood cells. Your cells are preserved. The plasma carrying harmful proteins and inflammatory molecules is discarded.

treat

Replace & Optimize

Your blood returns with a fresh replacement solution, which may include proteins, growth factors, and biologic compounds selected for your needs, precisely aimed at supporting repair and regeneration.

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The Dementia Question
Medicine Keeps Getting Wrong.

Most people with a family history of cognitive decline hear the same advice: eat well, stay active, and hope for the best. Dr. Haase believed patients deserved more than that. Building on research showing that optimizing the cellular environment helps stem cells behave as if they were younger, he developed Habitat Optimizing Plasma Exchange® in 2019. Today, patients travel from across the country for it, physicians nationwide refer their patients here, and Dr. Haase teaches the procedure to clinicians through national seminars and training programs. His TEDxNashville talk on regenerating hope for dementia asks the question this whole page is built on: what if we’ve been looking in the wrong place?

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See What Our Patients Have to Say.

I found out I had the Alzheimer's gene a few years ago… Because I have a family history of Alzheimer's, I knew these were early signs… I also started Therapeutic Plasma Exchange. This combination of treatments has given me balance again. My whole persona has changed. Now I'm more relaxed, and my mental clarity has improved. I can do things from memory that I couldn't do before. I feel 20 years younger, and I'm actually enjoying life again!

Gary S.

For 10 years I was told by conventional doctors that there was nothing they could do about my progressive weakness and nerve pain. I was losing my independence, and I felt hopeless. Then Dr. Haase introduced me to Therapeutic Plasma Exchange, and the results have been nothing short of life-changing. After only a few treatments, my pain decreased significantly… My balance has improved, I'm actually growing new muscle, and I have increased mental clarity. I feel like I got my life back.

Charles S.

After a series of Therapeutic Plasma Exchange treatments, my husband is a changed person! He's calmer and doesn't go off on tirades anymore. He has more energy and is more forgiving to all those around him. I feel such relief and am so grateful! We feel like we've got a second chance at life!

Cheryl S.

Individual results vary; testimonials are not claimed to represent typical results. Therapeutic Plasma Exchange may be one element of a treatment plan. Repeated plasma exchanges may be necessary.

Watch Dr. Haase Explain the Science of H.O.P.E.

In this presentation, Dr. Haase walks through how plasma exchange works, why it’s been trusted for decades, the science behind optimizing your body’s natural repair systems, and what patients are experiencing, from sharper cognition to reduced inflammation and renewed vitality. Whether you’re a patient searching for answers or a family member searching for options, start here.

Download the Brochure

What to Know Before You Accept "Wait and See."

Most families facing cognitive decline or chronic autoimmune disease are given a prescription and a follow-up date, and not much else. The free H.O.P.E. brochure walks you through how plasma exchange works, who it may help, what a treatment pathway looks like, and the questions to ask any provider before starting. Free. No appointment needed. Read it in 10 minutes.

Download H.O.P.E. Brochure
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What happens when you come in.

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Conversation

Your free consultation starts with the part most clinics skip: actually hearing your story. Your health history, your family history, what you’ve tried, and what you’re hoping to protect.

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Evaluation

A MaxWell clinician reviews your case and designs a personalized plan, including before-and-after testing: cognitive screens, Alzheimer’s biomarkers, inflammatory panels, or vascular and metabolic labs, matched to your pathway. We’re honest about candidacy. If H.O.P.E. isn’t a fit, we’ll tell you.

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Treatment, Measured

Your pathway pairs a series of plasma exchange procedures with clinician visits, IV nutrients, and targeted supplements. Changes aren’t only felt. They’re measured.

Four Pathways. One Goal:
a Healthier Habitat for Your Cells.

H.O.P.E. for Brain Health

For cognitive decline, MCI, and persistent brain fog.

  • 3 Clinician Visits
  • 6 H.O.P.E. procedures with IV nutrients
  • Pre & post testing: cognitive screens, Alzheimer's biomarkers, vascular/metabolic labs
  • Targeted supplements

H.O.P.E. for Autoimmunity

Calms chronic inflammation in complex autoimmune conditions.

  • 3 Clinician Visits
  • 6 H.O.P.E. procedures with IV nutrients
  • Pre & post testing: cognitive screens, Alzheimer's biomarkers, vascular/metabolic labs
  • Targeted supplements

H.O.P.E. for Detoxification

Helps lower post-viral or environmental toxin load.

  • 3 Clinician Visits
  • 6 H.O.P.E. procedures with IV nutrients
  • Pre & post testing: cognitive screens, Alzheimer's biomarkers, vascular/metabolic labs
  • Targeted supplements

H.O.P.E. for Longevity

Refreshes the cellular environment for healthy aging and peak performance.

  • 3 Clinician Visits
  • 6 H.O.P.E. procedures with IV nutrients
  • Pre & post testing: cognitive screens, Alzheimer's biomarkers, vascular/metabolic labs
  • Targeted supplements

Every plan is personalized, and pricing depends on your pathway. We keep our pricing below most centers in the country, at less than half the typical hospital charge, with package pricing available. Exact costs are discussed at your free consultation.

The Nation's Leader in Advanced Plasma Exchange.

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  • Group 102 Largest private outpatient apheresis center in the United States
  • Group 102 First to pioneer H.O.P.E.® in 2019, on 7+ years of clinical apheresis expertise
  • Group 102 Over 1,000 plasma exchanges performed
  • Group 102 Trusted by physicians nationwide who refer their patients here
  • Group 102 Patients travel from across the country for treatment
  • Group 102 Voted Best Holistic Clinic in Nashville, three years running

FAQs

Is plasma exchange safe?

Plasma exchange is considered very safe when performed in a medical setting, and it's been in clinical use since the 1950s. Side effects are possible but usually mild and manageable: temporary low calcium or magnesium, feeling chilled, or a brief drop in blood pressure. Our team monitors you throughout every procedure and responds immediately, which is part of why physicians across the country refer their patients to us.

Will insurance cover this?

MaxWell Clinic is an out-of-network provider and does not accept insurance. We provide receipts you can submit to your insurer, though reimbursement is not typical for this therapy. Many patients use HSA/FSA funds, and we offer package pricing. We'll walk you through exact costs before anything is scheduled.

How quickly do patients notice a difference?

It varies. Some patients notice changes like increased energy or clearer thinking after a few treatments; for others it develops more gradually. That's exactly why every pathway includes before-and-after testing, so you're not left guessing. We're transparent about expected timelines at your consultation.

How many treatments will I need?

It depends on your pathway and your response. Most pathways begin with 6 procedures over several weeks; the Longevity pathway starts with 2. In the large clinical trials on cognitive decline, benefit was shown with an initial weekly series followed by monthly treatments. We use the research as a starting point and customize from there.

What conditions can H.O.P.E. help?

Therapeutic plasma exchange is an established treatment for autoimmune and neurological conditions like myasthenia gravis, Guillain-Barré syndrome, and CIDP. Conditions with an autoimmune, degenerative, or neurologic component, including Alzheimer's, dementia, cognitive decline, and long-COVID hyperviscosity, have shown potential to improve. Your consultation determines whether it's appropriate for your situation.

Is everyone a candidate?

No, and we'll tell you that on day one. The free consultation is an evaluation, not a sales pitch. If H.O.P.E. isn't right for you, we'll point you toward what is.

You've already read this far. The brochure takes 10 minutes. The call takes 15. Both are free.

Download H.O.P.E. Brochure
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